National Journal of Maxillofacial Surgery

REVIEW ARTICLE
Year
: 2011  |  Volume : 2  |  Issue : 1  |  Page : 15--16

Oral lichen planus - Review on etiopathogenesis


K Srinivas, K Aravinda, P Ratnakar, Nitin Nigam, Siddharth Gupta 
 Department of Oral Medicine & Radiology, Career Postgraduate Institute of Dental Sciences & Hospital, Sitapur Road, Lucknow, India

Correspondence Address:
K Aravinda
Department of Oral Medicine & Radiology, Career Postgraduate Institute of Dental Sciences & Hospital, Sitapur Road, Lucknow - 226 020, Uttar Pradesh
India

Oral lichen planus (OLP) is a chronic mucocutaneous disease of uncertain etiopathogenesis. Several factors including stress, genetics, systemic diseases, viruses, dental restorative materials and drugs have been implicated as causative agents. The disease seems to be mediated by an antigen specific mechanism, activating cytotoxic T cells, and non specific mechanisms like mast cell degranulation and matrix metalloproteinase activation. Further clarity on the pathogenesis will aid in modifying therapeutic interventions, thus significantly reducing the morbidity of OLP patients.


How to cite this article:
Srinivas K, Aravinda K, Ratnakar P, Nigam N, Gupta S. Oral lichen planus - Review on etiopathogenesis.Natl J Maxillofac Surg 2011;2:15-16


How to cite this URL:
Srinivas K, Aravinda K, Ratnakar P, Nigam N, Gupta S. Oral lichen planus - Review on etiopathogenesis. Natl J Maxillofac Surg [serial online] 2011 [cited 2021 Aug 4 ];2:15-16
Available from: https://www.njms.in/article.asp?issn=0975-5950;year=2011;volume=2;issue=1;spage=15;epage=16;aulast=Srinivas;type=0