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National Journal of Maxillofacial Surgery
 
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CASE REPORT
Year : 2021  |  Volume : 12  |  Issue : 1  |  Page : 100-105

Severe insulin resistance syndrome – A rare case report and review of literature


1 Department of Pediatric Dentistry, Rural Dental College, Pravara Institute of Medical Sciences, Loni, Maharashtra, India
2 Department of Periodontics, Rural Dental College, Pravara Institute of Medical Sciences, Loni, Maharashtra, India
3 Department of Pediatric Dentistry, Karamveer Bhaurau Hiray Dental College, Mahatma Gandhi Vidyamandir, Nashik, Maharashtra, India

Correspondence Address:
Dr. Sourabh Ramesh Joshi
Department of Pediatric Dentistry, Rural Dental College, Pravara Institute of Medical Sciences, Loni - 413 736, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/njms.NJMS_55_20

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Insulin Resistance syndromes (IR's), are a group of genetic disorders caused due a functional defect in chromosome 19p13. It is an autosomal recessive condition. Donohue Syndrome was initially described by Donohue and Uchida in 1948 and 1954, a case of sisters born to parents with a first-degree consanguineous marriage. Infants presented with typical facial features that resembled the Leprechaun elves of Irish fairy tales. The following is a report of a rare case of dental complications of Severe Insulin Resistance Syndrome. An eight year old female child, with characteristic features of severe insulin resistance syndrome, reported to the Department of Pediatric and Preventive Dentistry, Pravara Institute of Medical Sciences, Loni, presenting with cariously destructed molars and a previous history of dental treatment under local anaesthesia. Given her condition, it was decided to reduce the multiple appointments, to one appointment with all procedures done under general anaesthesia. The following case report discusses the advantages, disadvantages and post operative complications faced when forming a treatment strategy for Severe Insulin Resistance Syndrome.


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