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| REVIEW ARTICLE |
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| Year : 2012 | Volume
: 3
| Issue : 2 | Page : 124-132 |
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Laser in dentistry: An innovative tool in modern dental practice
Sanjeev Kumar Verma, Sandhya Maheshwari, Raj Kumar Singh, Prabhat Kumar Chaudhari
Department of Orthodontics and Dental Anatomy, Aligarh Muslim University, Aligarh, India
| Date of Web Publication | 4-May-2013 |
Correspondence Address:
Sanjeev Kumar Verma
Department of Orthodontics and Dental Anatomy, Dr. Z. A. Dental College, Aligarh Muslim University, Aligarh - 212 001
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0975-5950.111342
 Abstract | | |
The term LASER is an acronym for 'Light Amplification by the Stimulated Emission of Radiation'. As its first application in dentistry by Miaman, in 1960, the laser has seen various hard and soft tissue applications. In the last two decades, there has been an explosion of research studies in laser application. In hard tissue application, the laser is used for caries prevention, bleaching, restorative removal and curing, cavity preparation, dentinal hypersensitivity, growth modulation and for diagnostic purposes, whereas soft tissue application includes wound healing, removal of hyperplastic tissue to uncovering of impacted or partially erupted tooth, photodynamic therapy for malignancies, photostimulation of herpetic lesion. Use of the laser proved to be an effective tool to increase efficiency, specificity, ease, and cost and comfort of the dental treatment. Keywords: Dental application, lasers, photostimulation
How to cite this article:
Verma SK, Maheshwari S, Singh RK, Chaudhari PK. Laser in dentistry: An innovative tool in modern dental practice. Natl J Maxillofac Surg 2012;3:124-32 |
How to cite this URL:
Verma SK, Maheshwari S, Singh RK, Chaudhari PK. Laser in dentistry: An innovative tool in modern dental practice. Natl J Maxillofac Surg [serial online] 2012 [cited 2022 Jul 2];3:124-32. Available from: https://www.njms.in/text.asp?2012/3/2/124/111342 |
| Introduction | |  |
Introduction of laser in dentistry, in the 1960s, by Miaman, [1] led to a continuous research in the various applications of lasers in dental practice. There are two scenarios, on the one hand there are hard lasers, such as, Carbon dioxide (CO 2 ), Neodymium Yttrium Aluminum Garnet (Nd: YAG), and Er:YAG, which offer both hard tissue and soft tissue applications, but have limitations [2],[3] due to high costs and a potential for thermal injury to tooth pulp, whereas, on the other hand in cold or soft lasers, based on the semiconductor diode devices, which are compact, low-cost devices used predominantly for applications, are broadly termed as low-level laser therapy (LLLT) or 'biostimulation'. [4] On account of the ease, efficiency, specificity, comfort, and cost over the conventional modalities, lasers are indicated for a wide variety [5],[6],[7],[8] of procedures in dental practice. The aim of this review is to focus on the hard as well as soft tissue applications, in dentistry.
| History | | |
In 1917, Albert Einstein [9] laid the foundation for the invention of the laser and its predecessor, 'the Maser,' by theorizing that photoelectric amplification could emit a single frequency, or stimulated emission. The term LASER is an acronym for 'Light Amplification by the Stimulated Emission of Radiation' and was first introduced to the public in 1959, in an article by a Columbia University graduate student, Gordon Gould. [10] Theodore Maiman, at the Hughes Research Laboratories in Malibu, CA, built the first functioning laser, [1] by using a mixture of helium and neon. In 1961, a laser generated from crystals of yttrium-aluminum-garnet treated with 1-3% neodymium (Nd: YAG) was developed. [10] In 1962, the argon laser was developed, whereas, the ruby laser became the first medical laser to coagulate retinal lesions, when it was used in 1963. [10] In 1964, Patel at Bell Laboratories developed the CO 2 laser. [10] Nowadays diode lasers are being extensively used in the field of dentistry.
| Types of Laser | | |
Lasers used in dental practice can be classified by various methods: According to the lasing medium used, such as, gas laser and solid laser; according to tissue applicability, hard tissue and soft tissue lasers; according to the range of wavelength [Figure 1], and of course the risk associated with laser application.
| Carbon dioxide Laser | | |
The CO 2 laser wavelength has a very high affinity for water, resulting in rapid soft tissue removal and hemostasis with a very shallow depth of penetration. Although it possesses the highest [11] absorbance of any laser, disadvantages of the CO 2 laser are its relative large size and high cost and hard tissue destructive interactions.
| Neodymium Yttrium Aluminum Garnet Laser | | |
The Nd: YAG wavelength is highly absorbed by the pigmented tissue, making it a very effective surgical laser for cutting and coagulating dental soft tissues, with good hemostasis. In addition to its surgical applications, [12] there has been research on using the Nd: YAG laser for nonsurgical sulcular debridement in periodontal disease control [13] and the Laser Assisted New Attachment Procedure (LANAP). [14]
| Erbium Laser | | |
The erbium 'family' of lasers has two distinct wavelengths, Er, Cr: YSGG (yttrium scandium gallium garnet) lasers and Er: YAG (yttrium aluminum garnet) lasers. The erbium wavelengths have a high affinity for hydroxyapatite and the highest absorption of water in any dental laser wavelengths. Consequently, it is the laser of choice for treatment of dental hard tissues. [15] In addition to hard tissue procedures, erbium lasers can also be used for soft tissue ablation, because the dental soft tissue also contains a high percentage of water. [16]
| Diode Laser | | |
The active medium of the diode laser is a solid state semiconductor made of aluminum, gallium, arsenide, and occasionally indium, which produces laser wavelengths, ranging from approximately 810 nm to 980 nm. All diode wavelengths are absorbed primarily by tissue pigment (melanin) and hemoglobin. Conversely, they are poorly absorbed by the hydroxyapatite and water present in the enamel. Specific procedures include aesthetic gingival re-contouring, soft tissue crown lengthening, exposure of soft tissue impacted teeth, removal of inflamed and hypertrophic tissue, frenectomies, and photostimulation of the apthous and herpetic lesions. [17]
| Mechanism of Laser Action | | |
Laser light is a monochromatic light and consists of a single wavelength of light. It consists of three principal parts: An energy source, an active lasing medium, and two or more mirrors that form an optical cavity or resonator. For amplification to occur, energy is supplied to the laser system by a pumping mechanism, such as, a flash-lamp strobe device, an electrical current, or an electrical coil. This energy is pumped into an active medium contained within an optical resonator, producing a spontaneous emission of photons. Subsequently, amplification by stimulated emission takes place as the photons are reflected back and forth through the medium by the highly reflective surfaces of the optical resonator, prior to their exit from the cavity via the output coupler [Figure 2]. In dental lasers, the laser light is delivered from the laser to the target tissue via a fiberoptic cable, hollow waveguide, or articulated arm [Table 1]. Focusing lenses, a cooling system, and other controls complete the system. The wavelength and other properties of the laser are determined primarily by the composition of an active medium, which can be a gas, a crystal, or a solid-state semiconductor.
The light energy produced by a laser can have four different interactions with a target tissue: [18],[19] Reflection, Transmission, Scattering, and Absorption [Figure 3]. When a laser is absorbed, it elevates the temperature and produces photochemical effects depending on the water content of the tissues. When a temperature of 100°C is reached, vaporization of the water within the tissue occurs, a process called ablation. At temperatures below 100°C, but above approximately 60°C, proteins begin to denature, without vaporization of the underlying tissue. Conversely, at temperatures above 200°C, the tissue is dehydrated and then burned, resulting in an undesirable effect called carbonization.
Absorption requires an absorber of light, termed chromophores, which have a certain affinity for specific wavelengths of light. The primary chromophores in the intraoral soft tissue are Melanin, Hemoglobin, and Water, and in dental hard tissues, Water and Hydroxyapatite. Different laser wavelengths have different absorption coefficients with respect to these primary tissue components, making the laser selection procedure-dependent. [20],[21],[22]
Depending on application on various tissues, use of laser application in dentistry can be categorized as follows: Soft tissue application and hard tissue application.
| Soft Tissue Application | | |
Wound healing
At low doses (e.g., 2 J/cm 2 ), laser application stimulates proliferation, while at high doses (e.g. 16 J/cm 2 ) it is suppressive. [23],[24] It affects fibroblast maturation and locomotion, [25] and this in turn may contribute to the higher tensile strengths reported for healed wounds. [26] Low-level laser treatment (LLLT) of gingival fibroblasts in the culture has been shown to induce transformation in myofibroblasts (useful in wound contraction) as early as 24 hours after laser treatment. [27] The positive effects of LLLT on the healing of lesions of recurrent aphthous stomatitis in humans have also been recorded. [28] There are some positive data, which indicate that LLLT promotes healing and dentinogenesis following pulpotomy, [29] as also the healing of mucositis and oropharyngeal ulcerations in patients undergoing radiotherapy for head and neck cancer. [30]
Post herpetic neuralgia and apthous ulcer
It has been demonstrated that photostimulation of aphthous ulcers and recurrent herpetic lesions, [31] with low levels of laser energy (HeNe) can provide pain relief and accelerate healing. [32],[33],[34],[35] In the case of recurrent herpes simplex labialis lesions, photostimulation during the prodromal (tingling) stage seems to arrest the lesions before painful vesicles form, accelerate the overall healing time, and decrease the frequency of recurrence. [36]
Photoactivated dye disinfection using lasers
Low power laser energy is useful for photochemical activation of oxygen-releasing dyes, causing membrane and DNA damage to the microorganisms. The photoactivated dye (PAD) technique can be undertaken with a system using low power (100 milliwatts) visible red semiconductor diode lasers and tolonium chloride (toluidine blue) dye. The PAD technique has been shown to be effective in killing bacteria in complex biofilms, such as, subgingival plaque, which are typically resistant to the action of antimicrobial agents [37],[38],[39] and can be made species-specific by tagging the dye with monoclonal antibodies. [40] Photoactivated dye can be applied effectively for killing Gram-positive bacteria (including Methicillin-resistant Staphylococcus aureus (MRSA)), Gram-negative bacteria, fungi, and viruses. [41],[42] The major clinical applications of PAD include disinfection of root canals, periodontal pockets, deep carious lesions, and sites of peri-implantitis. [43],[44] Tolonium chloride is used in high concentrations for screening patients, for malignancies of the oral mucosa and oropharynx. [45],[46]
Photodynamic therapy for malignancies
Photodynamic therapy (PDT), which has been employed in the treatment of malignancies of the oral mucosa, particularly multi-focal squamous cell carcinoma, acts on the same principle of PAD, and generates reactive oxygen species, which in turn, directly damages the cells and the associated blood vascular network, triggering both necrosis and apoptosis; [47] this activates the host immune response, and promotes anti-tumor immunity through the activation of macrophages and T lymphocytes. [48] There is direct evidence of the photodynamic activation of production of the tumor necrosis factor, alpha, [49] a key cytokine in host anti-tumor immune responses. Clinical studies have reported positive results for the PDT treatment of carcinoma in-situ and squamous cell carcinoma, in the oral cavity, with response rates approximating 90%. [50],[51]
Aesthetic gingival re-contouring and crown lengthening
With the advent of the diode laser, many clinicians are choosing to include optimization of gingival aesthetics as part of the comprehensive orthodontic treatment, [52],[53] whereas, conventional gingivectomy [Figure 4] is associated with pain, discomfort, and bleeding. | Figure 4: Aesthetic gingival contouring; a-e, pretreatment condition; b-c-f, after laser procedure; d, post treatment
Click here to view |
Exposure of unerupted and partially erupted teeth
An impacted or partially erupted tooth can be exposed for bonding by conservative tissue removal, allowing for reasonable positioning of a bracket or button [Figure 5]. It has the advantage of no bleeding, and an attachment can be placed immediately, and moreover, it is not painful at all. | Figure 5: Crown exposure; a-c-e, before exposure; b-d-f, after laser exposure
Click here to view |
Removal of inflamed, hypertrophic tissue, and miscellaneous tissue removal
Isolated areas of transient tissue hypertrophy can easily be excised with the diode laser without specialist referral [Figure 6]. The diode laser is also very useful for a number of isolated applications, such as, removing tissue that has overgrown mini-screws, springs [Figure 7]a and b, and appliances, [33] as well as for replacing a tissue punch if needed [Figure 7]c, when placing mini-screws in the unattached gingiva. | Figure 6: Removal of hyperplastic tissue; a-d, pretreatment; b-e, after laser
Click here to view |
 | Figure 7: (a and b) Exposure of embedded coil spring used during retraction; (c) a punch hole created for implant placement
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Frenectomies
A high or prominent labial frenum [Figure 8]a and b, when indicated, laser assisted frenectomy is a simple procedure that is best performed after the diastema is closed as much as possible. [32] Ankylosglossia [Figure 8]c and d can lead to problems with deglutition, speech, malocclusion, and potential periodontal problems. Frenectomies performed with a laser permit excision of the frena painlessly, without bleeding, sutures, or surgical packing, and with no need for special postoperative care.
| Hard Tissue Applications | | |
Photochemical effects
The argon laser produces high intensity visible blue light (488 nm), which is able to initiate photopolymerization of light-cured dental restorative materials, which use camphoroquinone as the photoinitiator. [54] Argon laser radiation is also able to alter the surface chemistry of both enamel and root surface dentine, [55] which reduces the probability of recurrent caries. The bleaching effect relies on the specific absorption of a narrow spectral range of green light (510-540 nm) into the chelate compounds formed between the apatites, porphyrins, and tetracycline compounds. [56] Argon and Potassium Titanyl Phosphate (KTiOPO 4 , KTP) lasers can achieve a positive result in cases that are completely unresponsive to conventional photothermal 'power' bleaching.
Laser fluorescence
Enamel demineralization with white spot formation on the buccal surfaces of the teeth is a relatively common side effect from orthodontic treatment with fixed appliances. [57],[58] There is evidence, however, which suggests that such small areas of superficial enamel demineralization may re-mineralize. [59]
Cavity preparation, caries, and restorative removal
Various studies depict the use of Er: YAG, since 1988, for removing caries in the enamel and dentine by ablation, without the detrimental effect of rise in temperature on the pulp, [60] even without water-cooling, [61] with low 'fluences' laser (LLLT), similar to air-rotor devices, except that the floor of the cavity is not as smooth. [62] The Er: YAG laser is capable of removing cement, composite resin, and glass ionomer. [63]
Etching
Laser etching has been evaluated as an alternative to acid etching of enamel and dentine. Enamel and dentine surfaces etched with (Er, Cr: YSGG) lasers show micro-irregularities and no smear layer. [64] Adhesion to dental hard tissues after Er: YAG laser etching is inferior to that obtained after conventional acid etching. [65],[66]
Treatment of dentinal hypersensitivity
Dentinal hypersensitivity is one of the most common complaints in clinical dental practice. Comparison of the desensitizing effects of an Er: YAG laser with those of a conventional desensitizing system on cervically exposed hypersensitive dentine [67] showed that desensitizing of hypersensitive dentine with an Er: YAG laser is effective, and maintenance of a positive result is more prolonged than with other agents.
Diagnostic application
The laser is being used for diagnostic purposes [Table 2] in clinical dental practice as well as in research purposes [Table 3]. | Table 3: Diagnostic laser applications used as research tools in dentistry
Click here to view |
3-D Laser scanner for e-model preparation
Our understanding of the growth of craniofacial structures is improving with the development of accurate, low-cost, 3-dimensional (3D) imaging systems, which can be classified as destructive or non-destructive devices, [68] hard or soft tissue imaging devices, [69] and contact or non-contact devices. [70] The laser scanner can be used as a soft tissue scanner and is a valuable tool for its ease of application and creation of 3D images of oral dental structures. There is no need of cast preparation as e-models are prepared from scanned impressions. Images have been created to establish databases for normative populations [71] and cross-sectional growth changes, [72] and also to assess the clinical outcomes in surgical [73],[74],[75] and non-surgical treatments [76],[77] in the head and neck regions.
| Miscellaneous Applications | | |
Analgesic effect of the laser
In vivo studies of the analgesic effect of LLLT on nerves supplying the oral cavity have shown that LLLT decreases the firing frequency of the nociceptors, with a threshold effect seen in terms of the irradiance required to exert maximal suppression. [78] There have been claims that successful analgesia following oral surgery can be achieved with all major LLLT wavelengths from 632 nm to 904 nm. [79],[80] Local CO 2 laser irradiation will reduce the pain associated with orthodontic force application, without interfering with tooth movement. [81],[82]
Nerve repair and regeneration
Low level laser therapy has been seen to reduce the production of inflammatory mediators of the arachadonic acid family from injured nerves, and to promote neuronal maturation and regeneration following injury. [83],[84] The LLLT protocols used, typically involve daily irradiation for prolonged periods, for example, 10 days at 4.5 J per day. [83] The direct application of this technique to dentistry has yielded positive results in promoting the regeneration of inferior dental nerve (IDN) tissue, damaged during surgical procedures.
Post surgical pain
A single episode of LLLT (irradiance 0.9-2.7 J) is 100% effective for apical periodontitis following root canal treatment and post-extraction pain. [85] There are conflicting results with regard to pain reduction post extraction by LLLT verses placebo controls. [86],[87],[88]
Sinusitis
There are conflicting findings on the benefit for sinusitis by laser therapy. One study [89] denies any significant benefit, while others found that LLLT improved microcirculation, reduced edema, and reduced the frequency of relapses. [90]
Of late, the diode laser has also been tried in experimental animals for controlling the excessive growth of the mandibular condyle. It was found that the laser is effective in regulating facial growth and could be a substitute for the current conventional methods such as a chin-cup. [91] McDonald and Pitt Ford found that the human pulpal blood flow was decreased when continuous light tipping forces were applied to a maxillary canine. [92] Barwick and Ramsay evaluated the effect of a four-minute application of intrusive orthodontic force on human pulpal blood flow with laser-Doppler flowmetry and concluded that the pulpal blood flow was not altered during the application of a brief intrusive orthodontic force. [93]
Recent studies have demonstrated that low-energy laser irradiation stimulates bone formation in vitro and in vivo. The macrophage colony-stimulating factor (M-CSF) is essential and sufficient for osteoclastogenesis. Low-energy laser irradiation stimulates the velocity of tooth movement via the expressions of M-CSF. [94]
Laser safety
While most dental lasers are relatively simple to use, certain precautions should be taken to ensure their safe and effective operation. [95] First and foremost is protective eyewear [Figure 9] by anyone in the vicinity of the laser, while it is in use. This includes the doctor, chairside assistants, patient, and any observers such as family or friends. It is critical that all protective eyewear worn is wavelength-specific. Additionally, accidental exposure to the non-target tissue can be prevented through the use of warning signs posted outside the nominal hazard zone, limiting access to the surgical environment, minimizing the reflective surfaces, and ensuring that the laser is in good working order, with all manufacturer safeguards in place. With regard to prevention of possible exposure to infectious pathogens, high volume suction should be used to evacuate any vapor plume created during tissue ablation, and normal infection protocols should be followed. Each office should have a designated Laser Safety Officer to supervise the proper use of the laser, coordinate staff training, oversee the use of protective eyewear, and be familiar with the pertinent regulations.
Medicolegal considerations
Conservative soft tissue surgery with a dental laser is considered within the scope of accepted dental practice and typically considered a covered procedure under most professional liability insurance policies designed for dental specialists. Informed consent must be routine and is best handled as part of the general consent form that all patients read and sign prior to the initiation of dental treatment. It is highly recommended that each clinician take a course from a reputable provider.
| Conclusion | | |
Laser technology for hard tissue application and soft tissue surgery is at a high state of refinement, having had several decades of development, up to the present time, and further improvements can occur. The field of laser-based photochemical reactions holds great promise for additional applications, particularly for targeting specific cells, pathogens, or molecules. A further area of future growth is expected to be a combination of diagnostic and therapeutic laser techniques. Looking to the future, it is expected that specific laser technologies will become essential components of contemporary dental practice over the next decade.
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[Figure 1], [Figure 2], [Figure 3], [Figure 4], [Figure 5], [Figure 6], [Figure 7], [Figure 8], [Figure 9]
[Table 1], [Table 2], [Table 3]
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Role of laser or photodynamic therapy in treatment of denture stomatitis: A systematic review |
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| Amin Davoudi,Behnaz Ebadian,Saeid Nosouhian | | The Journal of Prosthetic Dentistry. 2018; | | [Pubmed] | [DOI] | | | 60 |
Comparison of gingival depigmentation with Er,Cr:YSGG laser and surgical stripping, a 12-month follow-up |
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| Leila Gholami,Somayeh Ansari Moghaddam,Mohammad Ayoub Rigi Ladiz,Zohreh Molai Manesh,Hadi Hashemzehi,Alireza Fallah,Norbert Gutknecht | | Lasers in Medical Science. 2018; | | [Pubmed] | [DOI] | | | 61 |
Effect of Initiators on Thermal Changes in Soft Tissues Using a Diode Laser |
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| Georgios E. Romanos,Danielle Sacks,Nicholas Montanaro,Rafael Delgado-Ruiz,Jose Luis Calvo-Guirado,Fawad Javed | | Photomedicine and Laser Surgery. 2018; | | [Pubmed] | [DOI] | | | 62 |
Lasers in dentistry: an unceasing evolution |
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| Mithra N Hegde | | Journal of Otolaryngology-ENT Research. 2018; 10(6) | | [Pubmed] | [DOI] | | | 63 |
Awareness of Laser Dentistry Among Dentists in Tanjore- A survey |
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| Harini K,Radhika Arjunkumar | | Biomedical and Pharmacology Journal. 2018; 11(3): 1623 | | [Pubmed] | [DOI] | | | 64 |
Let the Light Heal - Lasers in Dentistry |
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| V. Susmitha, Visalakshi Nagappan, P. Arun Kumar Prasad | | Journal of Academy of Dental Education. 2018; 4: 8 | | [Pubmed] | [DOI] | | | 65 |
The Effect of Fluence Variations of Nd:YAG Laser Ablation and Sample Condition on Human Tooth |
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| Fatanah Mohamad Suhaimi,Nur Zarifha Zainol Alam,Suriani Mat Ariffin,Nurul Atiqah Abd. Razak,Mohammad Khairul Azhar Abdul Razab | | Advances in Science, Technology and Engineering Systems Journal. 2018; 3(5): 398 | | [Pubmed] | [DOI] | | | 66 |
Republication: Conservative Management of Skeletal Class II Malocclusion with Gummy Smile, Deep Bite, and a Palatally Impacted Maxillary Canine |
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| Ariel Wong,Chris Chang,W. Eugene Roberts | | APOS Trends in Orthodontics. 2018; 8: 146 | | [Pubmed] | [DOI] | | | 67 |
Applications of Laser Welding in Dentistry: A State-of-the-Art Review |
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| Asma Perveen,Carlo Molardi,Carlo Fornaini | | Micromachines. 2018; 9(5): 209 | | [Pubmed] | [DOI] | | | 68 |
Comparison of marginal microleakage of flowable composite restorations in primary canine teeth prepared with high-speed diamond bur, Er:YAG laser and Er,Cr:YSGG laser |
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| Beheshteh Malekafzali,Mohammad Asnaashari,Fateme Javadi | | LASER THERAPY. 2017; 26(3): 195 | | [Pubmed] | [DOI] | | | 69 |
In Vitro Comparison Of Fluoride Gel Alone and in Combination With Er,Cr:YSGG Laser on Reducing White Spot Lesions in Primary Teeth |
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| Fatemeh Molaasadollah,Mohammad Asnaashari,Fatemeh Mashhadi Abbas,Maral Jafary | | Journal of Lasers in Medical Sciences. 2017; 8(4): 160 | | [Pubmed] | [DOI] | | | 70 |
Laser Surgery of Soft Tissue in Orthodontics: Review of the Clinical Trials |
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| Massoud Seifi,Negin-Sadat Matini | | Journal of Lasers in Medical Sciences. 2017; 8(Suppl 1): S1 | | [Pubmed] | [DOI] | | | 71 |
The Effectiveness of Er.Cr.YSGG Laser in Sustained Dentinal Tubules Occlusion Using Scanning Electron Microscopy |
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| Al Hanouf Al Habdan | | Journal of Dental Health, Oral Disorders & Therapy. 2017; 7(6) | | [Pubmed] | [DOI] | | | 72 |
The Effect of Low Level Laser Therapy on Bone Healing After Rapid Maxillary Expansion: A Systematic Review |
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| Foteini G. Skondra,Despina Koletsi,Theodore Eliades,Eleftherios Terry R. Farmakis | | Photomedicine and Laser Surgery. 2017; | | [Pubmed] | [DOI] | | | 73 |
Comparison of effects of LLLT and LIPUS on fracture healing in animal models and patients: A systematic review |
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| Mohammad Bayat,Amarjit Virdi,Reza Jalalifirouzkouhi,Fatemehalsadat Rezaei | | Progress in Biophysics and Molecular Biology. 2017; | | [Pubmed] | [DOI] | | | 74 |
Comparison of the in vitro effects of low-level laser therapy and low-intensity pulsed ultrasound therapy on bony cells and stem cells |
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| Mohammad Bayat,Amarjit Virdi,Fatemehalsadat Rezaei,Sufan Chien | | Progress in Biophysics and Molecular Biology. 2017; | | [Pubmed] | [DOI] | | | 75 |
Phototherapy for treating foot ulcers in people with diabetes |
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| Hong-Tao Wang,Jin-Qiu Yuan,Bin Zhang,Mao-Long Dong,Chen Mao,Dahai Hu | | Cochrane Database of Systematic Reviews. 2017; | | [Pubmed] | [DOI] | | | 76 |
Er,Cr:YSGG Laser Application for the Treatment of Periodontal Furcation Involvements |
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| Linhua Ge,Yunxin Zhang,Rong Shu | | Photomedicine and Laser Surgery. 2016; | | [Pubmed] | [DOI] | | | 77 |
On-Site Surface Functionalization for Titanium Dental Implant with Nanotopography: Review and Outlook |
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| Byung Gyu Kim,Seog-Jin Seo,Jung-Hwan Lee,Hae-Won Kim | | Journal of Nanomaterials. 2016; 2016: 1 | | [Pubmed] | [DOI] | | | 78 |
The Effect of Energy Densities on the Shear Bond Strength of Self-Adhering Flowable Composite to Er:YAG Pretreated Dentin |
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| Paul Nahas,Toni Zeinoun,Zeina Majzoub,Karim Corbani,Samir Nammour | | BioMed Research International. 2016; 2016: 1 | | [Pubmed] | [DOI] | | | 79 |
Diode Laser Clinical Efficacy and Mini-Invasivity in Surgical Exposure of Impacted Teeth |
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| Mario Migliario,Manuela Rizzi,Alberta Greco Lucchina,Filippo Renò | | Journal of Craniofacial Surgery. 2016; 27(8): e779 | | [Pubmed] | [DOI] | | | 80 |
Methylene Blue-Mediated Photodynamic Inactivation Followed by Low-Laser Therapy versus Miconazole Gel in the Treatment of Denture Stomatitis |
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| Carolina Menezes Maciel,Marta Rabello Piva,Maria Amália Gonzaga Ribeiro,Thiago de Santana Santos,Cyntia Ferreira Ribeiro,Paulo Ricardo Saquete Martins-Filho | | Journal of Prosthodontics. 2016; 25(1): 28 | | [Pubmed] | [DOI] | | | 81 |
DERIN DENTIN ÇÜRÜKLERININ TEDAVISINDE ALTERNATIF YENI YÖNTEMLER |
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| Izgen HACIOGULLARI,Nuran ULUSOY,Esra CENGIZ | | Atatürk Üniversitesi Dis Hekimligi Fakültesi Dergisi. 2016; : 120 | | [Pubmed] | [DOI] | | | 82 |
The Versatility of 980 nm Diode Laser in Dentistry: A Case Series |
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| Nahid Derikvand,Zahra Chinipardaz,Sara Ghasemi,Nasim Chiniforush | | Journal of Lasers in Medical Sciences. 2016; 7(3): 205 | | [Pubmed] | [DOI] | | | 83 |
Application of Laser Irradiation for Restorative Treatments |
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| Amin Davoudi,Maryam Sanei,Hamid Badrian | | The Open Dentistry Journal. 2016; 10(1): 636 | | [Pubmed] | [DOI] | | | 84 |
Application of High-Power Diode Laser and Photodynamic Therapy in Endodontic Treatment - Review of the Literature |
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| Dejan Markovic,Dragana Rakaševic,Dijana Trišic | | Balkan Journal of Dental Medicine. 2015; 19(2) | | [Pubmed] | [DOI] | | | 85 |
Implementation of New Technologies in U.S. Dental School Curricula |
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| Sheri A. Brownstein,Aseel Murad,Ronald J. Hunt | | Journal of Dental Education. 2015; 79(3): 259 | | [Pubmed] | [DOI] | | | 86 |
The influence of a novel in-office tooth whitening procedure using an Er,Cr:YSGG laser on enamel surface morphology |
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| Dimitrios Dionysopoulos,Dimitrios Strakas,Eugenia Koliniotou-Koumpia | | Lasers in Surgery and Medicine. 2015; 47(6): 503 | | [Pubmed] | [DOI] | | | 87 |
Selective cytotoxic effects of low-power laser irradiation on human oral cancer cells |
|
| Wei-Zhe Liang,Pei-Feng Liu,Earl Fu,Hao-Sheng Chung,Chung-Ren Jan,Chih-Hsuan Wu,Chih-Wen Shu,Yao-Dung Hsieh | | Lasers in Surgery and Medicine. 2015; 47(9): 756 | | [Pubmed] | [DOI] | | | 88 |
Use of Lasers in the Management of Temporomandibular Disorders |
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| Vagish Kumar LS | | International Journal of Laser Dentistry. 2014; 4(2): 43 | | [Pubmed] | [DOI] | | | 89 |
Lasers in Prosthodontics—Part I: Implantology |
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| Tarun Kalra,Malvika Nagrath,Geeta Kalra | | International Journal of Laser Dentistry. 2014; 4(2): 49 | | [Pubmed] | [DOI] | | | 90 |
Erbium,Chromium:Yttrium-Scandium-Gallium-Garnet Laser-assisted Excision of Peripheral Giant Cell Granuloma |
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| Murali Tuppili,Butchi Babu,Uday Kiran Uppada,Sushma Naagmega,Ramesh Amirisetty | | International Journal of Laser Dentistry. 2014; 4(2): 54 | | [Pubmed] | [DOI] | | | 91 |
Excision of Intraoral Fibroepithelial Polyp using 940 nm Diode Laser |
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| Vidyaa Hari Iyer,Majety Sharath Chandragupta,Kalaimani Iyappan | | International Journal of Laser Dentistry. 2014; 4(2): 59 | | [Pubmed] | [DOI] | | | 92 |
Improving Denture-bearing Area using Diode Laser |
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| Kamalakanth Shenoy,Vidya Bhat,Sonia Sara Jacob | | International Journal of Laser Dentistry. 2014; 4(2): 64 | | [Pubmed] | [DOI] | |
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