National Journal of Maxillofacial Surgery

ORIGINAL ARTICLE
Year
: 2019  |  Volume : 10  |  Issue : 2  |  Page : 134--140

Health-related quality of life assessment for head-and-neck cancer patients during and at 3 months after radiotherapy – A prospective, analytical questionnaire-based study


Ahmad Masroor Karimi1, Munish Gairola2, Parveen Ahlawat2, Sarthak Tandon2, Manoj Pal3, Nishtha Sachdeva2, Muhammed Ismail Sharief2, Kiran Dobriyal2 
1 Department of Radiation Oncology, Cleveland Clinic, Cleveland, Ohio, USA
2 Department of Radiation Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, New Delhi, India
3 Department of Medical Oncology, Millennium Cancer Center, Gurugram, Haryana, India

Correspondence Address:
Dr. Parveen Ahlawat
Department of Radiation Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Sector-5, Rohini - 110 085, New Delhi
India

Introduction: Health-related quality of life (HRQoL) is a more specific area of QoL that deals with the evaluation and assessment of the impact of the disease and its treatment-related morbidities on a patient's physical, psychological, and social aspects. The aim of the present study was to assess the HRQoL of patients with head-and-neck cancer (HNCs) during and at 3 months after completion of radiotherapy (RT) by intensity-modulated RT. Materials and Methods: This study was a prospective, longitudinal, observational, and self-completed questionnaire-based study that included 120 patients with HNC who underwent intensity-modulated RT. The questionnaire had adequate internal consistency. The questionnaires were given to each patient at the beginning of treatment (pretreatment), weekly visits during the course of RT (at the end of 1st, 2nd, 3rd, 4th, 5th, and 6th week), on the day of completion of RT, and then finally at 3 months after completion of RT. Thus, a total of successive nine time points were assessed. Results and Conclusions: One hundred and eleven patients completed the questionnaires at all nine time points. HRQoL usually decreases during treatment and then increases to pretreatment levels by 3 months after treatment. The Quality of Life Questionnaire, Core Module and Quality of Life Questionnaire, Head and Neck Module were found to be both valid and reliable. There was a significant QoL reduction for the patients throughout treatment in relation to functions and symptoms in the treatment of HNC. However, all the functions and most of the symptoms returned to baseline at the 3-month follow-up.


How to cite this article:
Karimi AM, Gairola M, Ahlawat P, Tandon S, Pal M, Sachdeva N, Sharief MI, Dobriyal K. Health-related quality of life assessment for head-and-neck cancer patients during and at 3 months after radiotherapy – A prospective, analytical questionnaire-based study.Natl J Maxillofac Surg 2019;10:134-140


How to cite this URL:
Karimi AM, Gairola M, Ahlawat P, Tandon S, Pal M, Sachdeva N, Sharief MI, Dobriyal K. Health-related quality of life assessment for head-and-neck cancer patients during and at 3 months after radiotherapy – A prospective, analytical questionnaire-based study. Natl J Maxillofac Surg [serial online] 2019 [cited 2019 Dec 14 ];10:134-140
Available from: http://www.njms.in/article.asp?issn=0975-5950;year=2019;volume=10;issue=2;spage=134;epage=140;aulast=Karimi;type=0