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National Journal of Maxillofacial Surgery
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Year : 2014  |  Volume : 5  |  Issue : 2  |  Page : 180-183

Internal jugular vein thrombosis due to heterozygote methylene tetrahydrofolate reductase (MTHFR) 1298C and Factor V G1691A mutations after a minor trauma

Department of Otolaryngology and Head and Neck Surgery, The Ministry of Health, Izmir Tepecik Training and Research Hospital, Izmir, Turkey

Correspondence Address:
Murat Gumussoy
227 Sokak No. 15, A Block, Bayrakli - 35070, Izmir
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0975-5950.154824

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Internal jugular vein thrombosis usually appears in central venous catheterization, distant malignancies, hypercoagulation, infections, or secondary to ovarian hyperstimulation syndrome. A 44-year-old female patient presented to us with sore throat, and pain and swelling on the right side of her neck. She had a history of simple neck trauma 10 days ago. Ultrasonography and computed tomography showed bilateral multiple lymphadenopathies and right internal jugular vein thrombosis. Patient was put on parenteral antibiotherapy and oral anticoagulant treatment. Genomic DNA tests for hypercoagulation revealed methylene tetrahydrofolate reductase 1298C heterozygote mutation and Factor V G1691A (Leiden) mutation. Patient has been under clinical control for 1 year and does not have any complaints. In this article, diagnosis, treatment, and the etiology of internal jugular vein thrombosis, which is a rare and potentially fatal condition, have been discussed through this case.

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